Table 2.

Top down-regulated GO terms in hiPSC-CMs treated with ethanol compared with no treatment

ID	GO Term Description	Count	Fold Enrichment	P-value
GO:0005912	Adherens junction	44	6.53	4.41E-23
GO:0070161	Anchoring junction	44	6.37	1.13E-22
GO:0030054	Cell junction	56	4.18	1.57E-20
GO:0008092	Cytoskeletal protein binding	46	5.04	1.08E-19
GO:0030017	Sarcomere	24	13.14	4.80E-19
GO:0030016	Myofibril	25	12.14	4.94E-19
GO:0043228	Non-membrane-bounded organelle	93	2.38	1.12E-18
GO:0043232	Intracellular non-membrane-bounded organelle	93	2.38	1.12E-18
GO:0031674	I band	21	16.51	1.24E-18
GO:0015629	Actin cytoskeleton	33	7.28	1.70E-18
GO:0043292	Contractile fiber	25	11.49	1.80E-18
GO:0003779	Actin binding	32	7.48	2.85E-18
GO:0044449	Contractile fiber part	24	12.05	3.43E-18
GO:0005856	Cytoskeleton	64	3.21	6.86E-18
GO:0005925	Focal adhesion	30	7.90	9.69E-18
GO:0005924	Cell-substrate adherens junction	30	7.84	1.19E-17
GO:0030055	Cell-substrate junction	30	7.74	1.67E-17
GO:0030018	Z disc	18	15.71	1.55E-15
GO:0007010	Cytoskeleton organization	46	3.75	8.83E-15
GO:0005737	Cytoplasm	151	1.44	4.12E-14
GO:0003012	Muscle system process	27	6.22	1.85E-13
GO:0030029	Actin filament-based process	33	4.58	8.67E-13
GO:0005829	Cytosol	74	2.24	1.64E-12
GO:0005911	Cell-cell junction	30	4.80	4.18E-12
GO:0044822	Poly(A) RNA binding	43	3.33	4.61E-12
GO:0005515	Protein binding	158	1.36	4.66E-12
GO:0030036	Actin cytoskeleton organization	29	4.89	6.50E-12
GO:0005913	Cell-cell adherens junction	22	6.82	9.88E-12
GO:0050839	Cell adhesion molecule binding	26	5.23	2.6E-11
GO:0005198	Structural molecule activity	33	3.91	5.52E-11