Table 1.
Comparison | g | k | 95% CI | p | Q | df | p | I2 | RFSN | OFSN |
---|---|---|---|---|---|---|---|---|---|---|
All anxiety disorders vs. nonclinical comparison groups | 1.90 | 359 | [1.81, 1.98] | <.001 | 2508.03 | 358 | <.001 | 85.73 | 999754 | 5477 |
Anxiety disorders (excluding specific phobia) vs. nonclinical comparison groups | 2.01 | 333 | [1.92, 2.09] | <.001 | 2078.63 | 332 | <.001 | 84.03 | 957748 | 5381 |
GAD | 2.58 | 41 | [2.33, 2.83] | <.001 | 186.01 | 40 | <.001 | 78.50 | 18882 | 934 |
OCD | 1.82 | 79 | [1.67, 1.97] | <.001 | 373.95 | 78 | <.001 | 79.14 | 51713 | 1267 |
PD | 1.77 | 54 | [1.58, 1.97] | <.001 | 391.19 | 53 | <.001 | 86.45 | 24517 | 666 |
PTSD | 1.91 | 48 | [1.72, 2.11] | <.001 | 165.22 | 47 | <.001 | 71.55 | 14648 | 764 |
SAD | 2.28 | 77 | [2.12, 2.44] | <.001 | 300.76 | 76 | <.001 | 74.73 | 60076 | 1612 |
SP | 0.50 | 26 | [0.35, 0.64] | <.001 | 36.38 | 25 | .067 | 31.28 | 426 | 103 |
All depressive disorders vs. nonclinical comparison groups | 2.60 | 86 | [2.37, 2.83] | <.001 | 1293.93 | 85 | <.001 | 93.43 | 113446 | 1690 |
MDD | 2.74 | 76 | [2.49, 2.98] | <.001 | 1078.32 | 75 | <.001 | 93.05 | 94012 | 1602 |
Anxiety disorders vs. depressive disorders | −0.27 | 24 | [−0.45, −0.08] | .005 | 79.70 | 23 | <.001 | 71.14 | 124 | 27 |
Anxiety + depression vs. anxiety disorders | 0.75 | 11 | [0.37, 1.12] | <.001 | 46.11 | 10 | <.001 | 78.32 | 215 | 71 |
Anxiety + depression vs. depressive disorders | 0.47 | 10 | [0.29, 0.64] | <.001 | 5.57 | 9 | .782 | 0.00 | 46 | 37 |
Note. g = Hedges’s g; k = number of studies; CI = confidence interval; RFSN = Rosenthal’s fail-safe N; OFSN = Orwin’s fail-safe N; GAD = generalized anxiety disorder; OCD = obsessive-compulsive disorder; PD = panic disorder; PTSD = posttraumatic stress disorder; SAD = social anxiety disorder (generalized); SP = specific phobia; MDD = major depressive disorder
Anxiety-related disorders include GAD, OCD, PD, PTSD, SAD, SP, acute stress disorder, hoarding disorder, illness anxiety disorder, and social anxiety disorder (performance only).
Depressive disorders include MDD, minor depression, dysthymia, and depression not otherwise specified.
Anxiety + depression includes studies where a group was designated as having a comorbid anxiety disorder and depressive disorder.