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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Metabolism. 2020 Oct 12;113:154398. doi: 10.1016/j.metabol.2020.154398

Table 4.

Relative risk of NAFLD according to trajectories of body shape

Medium-stable Lean-moderate increase Lean-marked increase Medium-moderate increase Medium-marked increase
Cases, No. 378 522 807 511 551
Age-adjusted HR (95% CI) 1 (Reference) 1.11 (0.98-1.27) 3.61 (3.19-4.08) 3.21 (2.81-3.66) 4.68 (4.10-5.34)
Multivariable HR (95% CI)† 1 (Reference) 1.08 (0.94-1.23) 2.84 (2.50-3.22) 2.60 (2.27-2.98) 3.39 (2.95-3.89)
†

Adjusted for smoking status (never or past/current), total calories (kcal, quintiles), menopausal hormone therapy (never, past, current, premenopausal), Alternate Healthy Eating Index score (quintiles, missing), physical activity (quintiles), type 2 diabetes (yes or no), hypertension (yes/no), dyslipidemia (yes or no), physical activity (MET-hours/week, quintiles), regular use of aspirin (yes/no), and race (white/non-white).