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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2020 Jul 4;108(5):1229–1239. doi: 10.1016/j.ijrobp.2020.07.002

Table 3.

Univariable longitudinal Analysis of BAI and BDI associations with patient characteristics

BAI score
BDI score
Characteristic Estimate (95% CI) LRT P value Estimate (95% CI) LRT P value
Sex
 Male −3.06 (−6.97 to 0.85) .128 −0.12 (−3.56 to 3.32) .943
Age
 Continuous   0.02 (−0.18 to 0.22) .771 −0.04 (−0.24 to 0.15) .508
Highest education .063 .420
 High school   6.24 (1.14 to 11.3)   2.79 (−1.72 to 7.30)
 Graduate school   1.67 (−2.64 to 5.98) −0.10 (−4.02 to 3.82)
Ethnicity
 Non-Hispanic .732 .326
  Asian −4.79 (−13.2 to 3.64) −5.43 (−12.7 to 1.82)
  Black −5.18 (−19.3 to 8.93) −5.78 (−17.7 to 6.18)
  Middle Eastern   2.17 (−7.83 to 12.2)   5.34 (−3.09 to 13.8)
 Hispanic −1.40 (−7.67 to 4.87) −0.82 (−6.11 to 4.47)
History of anxiety
 Yes   6.35 (1.45–11.3) .015   5.27 (0.96–9.58) .020
History of depression
 Yes   4.38 (−0.91 to 9.67) .114   4.90 (0.39–9.41) .041
Baseline KPS .629 .855
 80 −2.31 (−11.1 to 6.51)   0.32 (−7.32 to 7.96)
 90   1.33 (−2.79 to 5.45)   1.03 (−2.69 to 4.75)
RT type
 Protons −3.43 (−7.74 to 0.88) .127 −2.41 (−6.13 to 1.31) .217
Glioma
 Yes   1.13 (−2.79 to 5.05) .579   1.93 (−1.40 to 5.26) .271
Seizures
 Yes   1.80 (−2.12 to 5.72) .375   3.47 (0.14-6.80) .043
Antiepileptic drugs
 Yes   0.44 (−3.42 to 4.36) .825   1.97 (−0.38 to 4.32) .251
Chemotherapy
 Yes   0.83 (−3.09 to 4.75) .680   1.33 (−2.00 to 4.66) .440
Surgery
 Yes −3.78 (−8.68 to 1.12) .137 −0.03 (−4.34 to 4.28) .989

Abbreviations: CI = confidence interval; KPS = Karnofsky performance status; LRT = likelihood ratio test; RT = radiation therapy.