Table 1.
The patients’ preoperative characteristics, anesthesia profiles and the drugs administered during anesthesia
| Control group (n = 63) | ALA group (n = 66) | P value | |
|---|---|---|---|
| Age (years) | 71 ± 11 | 74 ± 10 | 0.27 |
| Height (cm) | 162 ± 15 | 161 ± 14 | 0.58 |
| Weight (kg) | 65 ± 17 | 65 ± 18 | 0.97 |
| Sex (male/female) | 59 (94%)/4 (6%) | 55 (83%)/11 (17%) | 0.07 |
| Regular use of antihypertensive drug | 24 (38%) | 23 (35%) | 0.70 |
| Regular use of renin-angiotensin system inhibitor | 14 (22%) | 11 (17%) | 0.42 |
| Duration of surgery (minutes) | 43 ± 25 | 44 ± 20 | 0.84 |
| Duration of anesthesia (minutes) | 75 ± 28 | 80 ± 22 | 0.25 |
| Dose of 0.5% hyperbaric bupivacaine of spinal anesthesia (mL) | 3.1 ± 0.3 | 3.0 ± 0.3 | 0.20 |
| Sensory block level just before surgerya | T8 (T2–T11) | T6 (T2–L1) | 0.26 |
| Sensory block level at the end of surgerya | T6 (T2–T12) | T5 (T2–T12) | 0.49 |
| Intravenous fluid volume during anesthesia (mL) | 570 ± 191 | 758 ± 284 | < 0.001 |
| Use of vasopressorsb | 10 (16%) | 47 (71%) | < 0.001 |
| Use of ephedrine | 8 (13%) | 37 (56%) | < 0.001 |
| Total dose of ephedrine (mg) | 1.0 ± 3.0 | 6.9 ± 9.0 | < 0.001 |
| Use of phenylephrine | 6 (10%) | 30 (45%) | < 0.001 |
| Total dose of phenylephrine (mg) | 0.013 ± 0.042 | 0.21 ± 0.34 | < 0.001 |
Values are presented as mean ± standard deviation or number (%)
aMedian (maximum-minimum)
bEphedrine or phenylephrine or both were used
ALA aminolevulinic acid