Table 3.
Glycolysis pathways involved DEPs operated in ovarian cancer biological system
| Pathway code | Accession no. | Protein | calc. pI | MW (kDa) | Ratio (T/N) | p value (t test) |
|---|---|---|---|---|---|---|
| 1.1.1.1 | P11766 | Alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5) | 7.5 | 39.70 | 0.50 | 6.60E-05 |
| 4.2.1.11 | P06733 | Enolase 1 (ENO1) | 7.4 | 47.14 | 1.59 | 2.60E-11 |
| 5.3.1.9 | K7EQ48 | Glucose-6-phosphate isomerase (GPI) | 8.7 | 53.37 | 1.31 | 2.96E-02 |
| 1.2.1.12 | P04406 | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) | 8.5 | 36.03 | 1.85 | 2.24E-44 |
| 1.1.1.27 | P00338 | Lactate dehydrogenase A (LDHA) | 8.3 | 36.67 | 1.56 | 4.00E-04 |
| 1.1.1.27 | P07195 | Lactate dehydrogenase B (LDHB) | 6.1 | 36.62 | 1.50 | 6.40E-03 |
| 2.7.1.11 | Q01813 | Phosphofructokinase, platelet (PFKP) | 7.5 | 85.54 | 1.90 | 2.28E-02 |
| 2.7.1.40 | A0A024R5Z9 | Pyruvate kinase, muscle (PKM) | 7.7 | 58.02 | 2.38 | 1.50E-04 |
Ratio (T/N) means the ratio of tumor to control
DEPs, differentially expressed proteins; pI, isoelectric point; MW, molecular weight