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. 2020 Nov 17;13:11795–11806. doi: 10.2147/OTT.S274492

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© 2020 Yang et al.

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ZFAS1 sequestered miR-647 in a m⁶A-dependent manner. (A) The MeRIP assay was used to measure the m⁶A modification of ZFAS1. (B) The ZFAS1 expression in control and METTL3 knockdown Caski and Hela cells. (C) The m⁶A level of ZFAS1 in control and METTL3 knockdown Caski and Hela cells. (D) The METTL3 knockdown abolished the ZFAS1-induced suppression of miR-647. (E) The METTL3 protein level in in control and METTL3 knockdown Caski cells. (F) The METTL3 knockdown abolished the miR-647-mediated inhibition of luciferase activity of ZFAS1 reporter. *p<0.05, **p<0.01, ***p<0.001.