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. 2020 Nov 18;13:1635–1648. doi: 10.2147/JMDH.S279031

Table 3.

General Management of COVID-19 Using Ventilatory Support (N= 502)*

Characteristics Values
Initial flow setting of HFNC
  ● Below 30 L/m 90 (17.9%)
  ● From 30 to 45 L/m 150 (29.9%)
  ● More than 45 L/m 80 (15.9%)
 Use of humidification with HFNC 309 (61.6%)
NIV modes
  • BiPAP

161 (32.1%)
  • CPAP/PS

204 (40.6%)
  • PC

43 (8.6%)
  • VC

19 (3.8%)
NIV interfaces frequently used
  • Full face mask

192 (38.2%)
  • Helmet

67 (13.3%)
  • Nasal mask

19 (3.8%)
  • Oronasal mask

154 (30.7%)
IMV modes
  ● APRV 39 (7.8%)
  ● PC 175 (34.9%)
  ● PRVC 107 (21.3%)
  ● VC 181 (36.1%)
Humidifier type used with IMV
  ● Heated circuit 135 (26.9%)
  ● HEPA 11 (2.2%)
  ● HME 356 (70.9%)
Ventilation strategy used in IMV
  ● Low VT ventilation (VT: 4–8 ml/kg of predicted body) 481 (96%)
  ● Higher VT ventilation (VT>8 ml/kg of predicted body weigh) 20 (4%)
PEEP strategy
 ● Lower PEEP (PEEP levels <10 cm H2O) 182 (36.3%)
 ● Higher PEEP (PEEP levels >10 cm H2O) 320 (63.7%)
 Use of prone with IMV 430 (85.7%)
Prone duration
  • <12 hours/day

74 (14.7%)
  • 12 to 16 hours/day

243 (48.4%)
 ● >16 hours/day 116 (23.1%)
Reasons for not proning
  ● Limited resources 61 (12.2%)
  ● Lack of staff training 71 (14.9%)
  ● Complications 67 (13.3%)
  ● Not indicated 64 (12.7%)
 Tried awake prone positioning 232 (46.2%)
 Frequent use of nitric oxide 61 (12.2%)
 Use inhaled pulmonary vasodilator 191 (38%)
 Use of recruitment manoeuvres 349 (69.5%)
Recruitment manoeuvres used
 ● Stepwise PEEP adjustment 214 (42.6%)
 ● Inspiratory hold 146 (29.1%)
 Use of (VV) ECMO 97 (19.3%)
 Use of systemic corticosteroids 323 (64.3%)

Note: *All percentages are expressed corresponding to the total number of respondents.

Abbreviations: APRV, airway pressure release ventilation; BIPAP, bilevel positive airway pressure; CPAP/PS, continuous positive airway pressure/pressure support; HME, heat and moisture exchanger; HEPA, high-efficiency particulate air; PEEP, positive end-expiratory pressure; PC, pressure control; PRVC, pressure regulated volume control; Vt, tidal volume; VV, venovenous; VC, volume control.