Male, 33yrs, Secondary Malignancy in Giant Cell Tumhttps://elsevier.proofcentral.com/en-us/landing-page.html?token=aa2295e304800f3831fd002effa727or of Bone. Anteroposterior knee joint radiograph (Fig. 3-A from 2001) showing osteolytic lesion at the medial tibial platform, CT-scan (Fig. 3-B from 2001) illustrating the well-circumscribed lesion without cortical destruction. This lesion was treated with curettage and bone graft, complaint of pain and swelling eight years later, a local “recurrence” was diagnosed. Coronal (Fig. 3-C from 2009) and axial of CT-scan (Fig. 3-D from 2009) demonstrating a sclerotic and destructive relapse involving the tibial platform, with cortical bone breakthrough, soft tissue mass involvement and significant enhancement in contrast CT-scan.