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. 2020 Nov 9;8:583336. doi: 10.3389/fpubh.2020.583336

Table 3.

Expansion and definition of HRV measurement acronyms.

Measurement Units Expansion Application Interpretation
RMSSD ms Root-mean square of successive differences Primary measurement for short-term vagally mediated changes (2) Time-Domain Measurements generally increase with increased aerobic capacity (2, 47)
pNN20 % Percentage of adjacent intervals that differ by more than 20 ms Assessment of vagal activity (2)
Thresholds of ~6.8% or lower for disease states have been posited (48, 49)
pNN50 % Percentage of adjacent intervals that differ by more than 50 ms
AVNN ms Average value N-N; mean interbeat interval Sensitive to changes in Psychological stress (50)
SDNN (SDRR) Ms Standard deviation of all interbeat intervals during the sample period Most widely acceptable HRV measurement for assessing cardiac risk (24-h recording only) (2)
VLF ms2 Very-Low Frequency Band power (0.0033-0.04 Hz) Intrinsically generated by the heart (2)
Modulated by sympathetic activity (2)
Low VLF power has been associated with cardiac death, PTSD and inflammation (2, 51)
LF ms2 Low Frequency Band power (0.04-0.15 Hz) Represents baroreceptor activity during resting measurements (2) Can be used to estimate vagal tone (2, 52)
LnLF nu Natural log of LF Relative frequency band measurement to total power (53)
HF ms2 High Frequency Band power (0.15-0.4 Hz) Parasympathetic and respiratory activity (2) Low HF values are associated with high stress (50)
Correlated with RMSSD (2)
LnHF nu Natural log of HF Relative frequency band measurement to total power (53)
LF/HF % Ratio of LF to HF power For resting seated measurements, likely measures PNS and baroreceptor activity (2) Highly dependent on measurement conditions (2)
TP ms2 Total Spectral power Useful for determining relative power measurements (2) Broad estimate of total autonomic activity (2)
SD1 ms Standard Deviation from y-axis on Poincare plot Nonlinear measurement, useful for short-term analysis without trend sensitivity (2) Predicts RMSSD, pNN50, SDNN, and power in the LF and HF bands, and total power during 5 min recordings (2, 52)
SD2 ms Standard Deviation from x-axis on Poincare plot Nonlinear measurement, useful for long-term analysis without trend sensitivity (2) Correlates with LF power (2)
SampEn Sample entropy or approximate entropy Quantification of the unpredictability of a time series (2) Useful for short recordings which may have noise (2)
Alpha1 Short-term detrended fluctuation analysis
Extracts the correlations between successive RR intervals over different time scales
Reflects baroreflex activity (2) Useful when longer recordings are not available (2)