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. 2020 Nov 17;14:4975–4992. doi: 10.2147/DDDT.S279553

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© 2020 Gao et al.

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Model effect validation and MGNC effects on stress management and ovarian reserve. (A) Average body weight of mice in different groups changes during the 8-week CUS stress paradigm. (B) Serum CORT level of mice in each group. (C) The percentage of time (days) at four estrous phases in the last three weeks of the stress paradigm. (D) The number of follicles at different stages in mice ovaries. Primordial: primordial follicles; primary: primary follicles; secondary: secondary follicles; antral: antral follicles; atretic: atretic follicles; luteum: corpus luteum. *: P<0.05 compared with C group, #: P<0.05 compared with M group, ▲: P<0.05 compared with N group.