TABLE 4.

Lists of the GSEA leading edge core genes that account for the enrichment of the GO biological process “Blood Coagulation” (GO: 0007596).

MXW vs. GMA		CTW vs. GMA
GSEA NES 2.l FDR 0.003; nominal p-value < 0.01		GSEA NES 1.74 FDR 0.146;nominal p-value < 0.01
PLAT	Plasminogen activator, tissue type	PLAT	Plasminogen activator, tissue type
F7	Coagulation factor VII	TFPl	Tissue factor pathway inhibitor
TFPl	Tissue factor pathway inhibitor	PF4	Platelet factor 4
GNAQ	G protein subunit alpha q	F7	Coagulation factor VII
PF4	Platelet factor 4	F12	Coagulation factor XI I
F2	Coagulation factor II, thrombin	ITGA2	Integrin subunit alpha 2
LMAN1	Lectin, mannose-binding 1	F2	Coagulation factor II, thrombin
F5	Coagulation factor V	PROSl	Protein S
PLG	Plasminogen	PLG	Plasminogen
F12	Coagulation factor XI I	WAS	WASP actin nucleation promoting factor
WAS	WASP actin nucleation promoting factor
C4BPB	Complement component 4 binding protein beta
TMPRSS6	Transmembrane serine protease 6

Normalized Enrichment score (NES), FDR and nominal p-value were reported for each comparison.