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. 2020 Nov 9;11:579964. doi: 10.3389/fgene.2020.579964

TABLE 6.

List of the GSEA leading edge core genes that account for the enrichment of the GO biological process “Female Pregnancy” (GO: 0007565).

MXW vs. GMA
CTW vs. GMA
MXW vs. CTW
NES 1.9 FDR 0.04 nominal p-value < 0.01 NES 1.68 FDR 0.17 nominal p-value < 0.01 NES 1.72 FDR 1 nominal p-value < 0.01
AGT Angiotensinogen AGT Angiotensinogen HPGD 15-hydroxyprostaglandin dehydrogenase
CRH Corticotropin releasing hormone CSH2 Chorionic somatomammotropin hormone 2 CRH Corticotropin releasing hormone
TAC3 Tachykinin precursor 3 TAC3 Tachykinin precursor 3 PSG7 Pregnancy specific beta-1-glycoprotein 7
HPGD 15-hydroxyprostaglandin dehydrogenase PPARD Peroxisome proliferator activated receptor delta PSG5 Pregnancy specific beta-1-glycoprotein 5
COL16A1 Collagen type XVI alpha 1 chain CRH Corticotropin releasing hormone PSG4 Pregnancy specific beta-1-glycoprotein 4
PSG5 Pregnancy specific beta-1-glycoprotein 5 SPRR2D Small proline rich protein 2D COL16A1 Collagen type XVI alpha 1 chain
PSG7 Pregnancy specific beta-1-glycoprotein 7 COL16A1 Collagen type XVI alpha 1 chain AGT Angiotensinogen
PSG9 Pregnancy specific beta-1-glycoprotein 9 PRLHR Prolactin releasing hormone receptor PSG11 Pregnancy specific beta-1-glycoprotein 11
GHRL Ghrelin and obestatin prepropeptide ADM Adrenomedullin PSG8 Pregnancy specific beta-1-glycoprotein 8
CSH2 Chorionic somatomammotropin hormone 2 TAC3 Tachykinin precursor 3
ADM Adrenomedullin SCGB1A1 Secretoglobin family 1A member 1
FCGRT Fc fragment of IgG receptor and transporter PSG6 Pregnancy specific beta-1-glycoprotein 6
TFCP2L1 Transcription factor CP2 like 1 PSG1 Pregnancy specific beta-1-glycoprotein 1
PSG8 Pregnancy specific beta-1-glycoprotein 8 PSG9 Pregnancy specific beta-1-glycoprotein 9
PSG1 Pregnancy specific beta-1-glycoprotein 1
SCGB1A1 Secretoglobin family 1A member 1
PSG6 Pregnancy specific beta-1-glycoprotein 6
PSG11 Pregnancy specific beta-1-glycoprotein 11
GHSR Growth hormone secretagogue receptor
SPRR2D Small proline rich protein 2D

Normalized Enrichment Score (NES), FDR and nominal p-value were reported for each comparison.