TABLE 6.
List of the GSEA leading edge core genes that account for the enrichment of the GO biological process “Female Pregnancy” (GO: 0007565).
| MXW vs. GMA |
CTW vs. GMA |
MXW vs. CTW |
|||
| NES 1.9 FDR 0.04 nominal p-value < 0.01 | NES 1.68 FDR 0.17 nominal p-value < 0.01 | NES 1.72 FDR 1 nominal p-value < 0.01 | |||
| AGT | Angiotensinogen | AGT | Angiotensinogen | HPGD | 15-hydroxyprostaglandin dehydrogenase |
| CRH | Corticotropin releasing hormone | CSH2 | Chorionic somatomammotropin hormone 2 | CRH | Corticotropin releasing hormone |
| TAC3 | Tachykinin precursor 3 | TAC3 | Tachykinin precursor 3 | PSG7 | Pregnancy specific beta-1-glycoprotein 7 |
| HPGD | 15-hydroxyprostaglandin dehydrogenase | PPARD | Peroxisome proliferator activated receptor delta | PSG5 | Pregnancy specific beta-1-glycoprotein 5 |
| COL16A1 | Collagen type XVI alpha 1 chain | CRH | Corticotropin releasing hormone | PSG4 | Pregnancy specific beta-1-glycoprotein 4 |
| PSG5 | Pregnancy specific beta-1-glycoprotein 5 | SPRR2D | Small proline rich protein 2D | COL16A1 | Collagen type XVI alpha 1 chain |
| PSG7 | Pregnancy specific beta-1-glycoprotein 7 | COL16A1 | Collagen type XVI alpha 1 chain | AGT | Angiotensinogen |
| PSG9 | Pregnancy specific beta-1-glycoprotein 9 | PRLHR | Prolactin releasing hormone receptor | PSG11 | Pregnancy specific beta-1-glycoprotein 11 |
| GHRL | Ghrelin and obestatin prepropeptide | ADM | Adrenomedullin | PSG8 | Pregnancy specific beta-1-glycoprotein 8 |
| CSH2 | Chorionic somatomammotropin hormone 2 | TAC3 | Tachykinin precursor 3 | ||
| ADM | Adrenomedullin | SCGB1A1 | Secretoglobin family 1A member 1 | ||
| FCGRT | Fc fragment of IgG receptor and transporter | PSG6 | Pregnancy specific beta-1-glycoprotein 6 | ||
| TFCP2L1 | Transcription factor CP2 like 1 | PSG1 | Pregnancy specific beta-1-glycoprotein 1 | ||
| PSG8 | Pregnancy specific beta-1-glycoprotein 8 | PSG9 | Pregnancy specific beta-1-glycoprotein 9 | ||
| PSG1 | Pregnancy specific beta-1-glycoprotein 1 | ||||
| SCGB1A1 | Secretoglobin family 1A member 1 | ||||
| PSG6 | Pregnancy specific beta-1-glycoprotein 6 | ||||
| PSG11 | Pregnancy specific beta-1-glycoprotein 11 | ||||
| GHSR | Growth hormone secretagogue receptor | ||||
| SPRR2D | Small proline rich protein 2D | ||||
Normalized Enrichment Score (NES), FDR and nominal p-value were reported for each comparison.