Table 3.
Comparison of the basic condition of patients between 28-day survivors and non-survivors (n,%).
| Characteristics | Survivors (n = 170) | Non-survivors (n = 127) | p |
|---|---|---|---|
| Gender (male, %)∫ | 116 (68.2) | 86 (67.7) | 0.924 |
| Age (Years, Mean ± SD)∬ | 54 ± 16 | 55 ± 15 | 0.625 |
| Hospital before∫ | 76 (44.7) | 73 (57.4) | 0.029 |
| ICU before∫ | 39 (22.9) | 74 (58.2) | <0.001 |
| Recent surgical history∫ | 51 (30) | 54 (42.5) | 0.026 |
| Invasive operation∫ | |||
| CVC | 57 (33.5) | 87 (68.5) | <0.001 |
| Subclavian vein | 35 (61.4) | 54 (62.1) | 0.936 |
| Internal jugular vein | 18 (31.6) | 28 (32.2) | 0.939 |
| Femoral vein | 3 (5.3) | 6 (6.9) | 0.692 |
| Dialysis tube | 14 (8.2) | 32 (25.2) | <0.001 |
| Arteriopuncture | 89 (52.4) | 94 (74) | <0.001 |
| Trachea cannula | 21 (12.3) | 66 (51.9) | <0.001 |
| Tracheotomy | 9 (5.2) | 23 (18.1) | 0.022 |
| Thoracentesis | 4 (2.3) | 12 (9.4) | 0.007 |
| Abdominocentesis | 8 (4.7) | 10 (7.9) | 0.258 |
| Lumbar puncture | 10 (5.9) | 13 (10.2) | 0.165 |
| Bone marrow aspiration | 18 (10.6) | 17 (13.4) | 0.459 |
| Indwelling catheter | 82 (48.2) | 86 (67.7) | 0.001 |
| Indwelling gastric tube | 48 (28.2) | 72 (56.7) | <0.001 |
| Organ transplantation∫ | 4 (2.3) | 5 (3.9) | 0.656 |
| Application of antibiotics∫ | 59 (34.4) | 37 (29.1) | 0.310 |
| Glucocorticoid∫ | 9 (5.2) | 9 (7.1) | 0.522 |
| Immunosuppressant∫ | 12 (7.1) | 10 (7.8) | 0.791 |
| Hospital infection∫ | 94 (55.2) | 63 (53.5) | 0.764 |
| Hospital days before infection∭ | 8 [4,18] | 14 [5,22] | 0.015 |
| Pitt bacteremia score (median [IQR])∭ | 2 [0,4] | 2 [0,5] | 0.577 |
| Charlson comorbidity index (median [IQR])∭ | 3 [2,5] | 3 [1,4] | 0.277 |
| Basic diseases∫ | |||
| Hypertension | 47 (27.6) | 39 (30.7) | 0.565 |
| Diabetes | 26 (15.2) | 43 (33.8) | <0.001 |
| Chronic renal failure | 18 (10.5) | 29 (22.8) | 0.004 |
| Liver insufficiency | 21 (12.3) | 26 (20.4) | 0.058 |
| Solid Organ Cancer | 23 (13.5) | 13 (10.2) | 0.390 |
| Blood disease | 20 (11.7) | 20 (15.7) | 0.320 |
| Coronary heart disease | 24 (14.1) | 34 (26.7) | 0.006 |
| Respiratory failure∫ | 23 (13.5) | 37 (29.1) | 0.001 |
| Hypoalbuminemia∫ | 34 (20) | 56 (44) | <0.001 |
| Drug resistance (S-KP, %)∫ | 88 (51.7) | 26 (20.4) | <0.001 |
| Drug resistance (MDR-KP, %)∫ | 56 (32.9) | 43 (33.8) | 0.868 |
| Drug resistance (XDR-KP, %)∫ | 26 (15.2) | 58 (45.6) | <0.001 |
| Septic shock∫ | 15 (8.8) | 48 (37.7) | <0.001 |
| MODS∫ | 9 (5.2) | 39 (30.7) | <0.001 |
| APACHEII score∭ | 7 [4,11] | 18 [13,23] | <0.001 |
| SOFA score∭ | 2 [2,4] | 8 [5,11] | <0.001 |
| Mechanical ventilation∫ | 23 (13.5) | 72 (56.6) | <0.001 |
∫Use Chi-Square Test to verify; ∬Two groups were compared with independent t-test; ∭Use Mann-Whitney U Test to verify.
SD Standard deviation, ICU intensive care unit, CVC central venous catheter, IQR inter-quartile range, MODS multiple organ dysfunction syndrome, APACHE acute physiology and chronic health evaluation, SOFA sequential organ failure assessment, S-KP sensitive K. pneumoniae, MDR-KP multidrug resistant K. pneumoniae, XDR-KP extensively drug resistant K. pneumoniae.