Figure 1.

(a) Schematic representation of the generation method of PB‐modified hGMR‐CAR T cells. PBMCs were transfected with hGMR‐CAR via the piggyBac transposon system. On day 3, the cells were cocultured with iDCs derived from PBMCs with interleukin (IL)‐4 and GM‐CSF for 72 h. The electroporated T cells were cultured with IL‐7 and IL‐15. Fourteen days after culture initiation, cells were harvested and analysed. (b) Expression of human or cynomolgus hGMR‐CAR T cells. (c) Representative flow cytometry results each cynomolgus and human hGMR‐CAR T cells. (d) Characterisation of cynomolgus hGMR‐CAR T cells.