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. Author manuscript; available in PMC: 2020 Nov 23.
Published in final edited form as: Biochem Pharmacol. 2019 Aug 14;169:113604. doi: 10.1016/j.bcp.2019.08.006

Figure 10. A pharmacological CSE inhibitor increases, while supplementation of exogenous H2S decreases CPOX promoter activity in cultured liver cells.

Figure 10.

A CPOX luciferase reporter construct was established in HepG2 liver cells. Addition of the pharmacological inhibitor of CSE (PAG) or NaHS exerted stimulatory vs. inhibitory effects on CPOX promoter/gene activity. In this assay, the negative and postive control vectors were provided and used according to manufacturer’s instructions. CTL group showed basic CPOX promoter activity. Data are shown as mean ± SEM of n=6 repeats. *p<0.05, **p<0.01 vs. CTL group.