Figure 5. Increased CPOX protein expression in liver tissues of CSE−/− mice.
(A, B) Western blot analysis of liver homogenates of CSE−/− vs. wild-type mice confirmed (1) lack of CSE, (2) increased CPOX and Tom 20, and (3) no alterations of CBS, 3-MST, and TST protein levels. (C) H2S production by CSE was completely absent in liver tissue homogenates from CSE−/− mice. Data are shown as mean ± SEM of CSE−/− and wild-type mice using n=3 animals/group. *p<0.05, **p<0.01 vs. wild-type group.