Table 3: No significant differences in blood gas parameters of CSE^−/− and wild-type mice.

Glucose, HCO₃, pO₂, pCO₂, lactate, pH, and total hemoglobin were determined from arterial blood. pO₂, pCO₂, lactate, and pH were measured from venous blood. Data show significant increase in hemoglobin level of CSE^−/− mice (13±0.4, n=6) compared to the wild-type group (12±0.4, n=6). No significant differences in lung functions (qs/Qt, PaO₂/FiO₂) were noted between CSE^−/− and wild-type mice.

Blood gas parameters	Wild-type			CSE−/−
	Mean	SEM	n	Mean	SEM	n	p value
Arterial blood
glucose (mg/dL)	206	8	6	182	19	6	0.29
HCO3 (mmol/L)	18,0	0,4	6	18,1	1,1	6	0.93
pO2 (mmHg)	116,6	3,5	6	109,9	8,5	6	0.48
pCO2 (mmHg)	29,6	1,3	6	29,3	1,6	6	0.89
lactate (mmol/L)	3,0	0,3	6	2,7	0,2	6	0.54
pH	7,39	0,02	6	7,40	0,0	6	0.86
total Hb (g/dL)	12,5	0	6	13,5	0,3	6	0.043*
Venous blood
pO2 (mmHg)	42,7	3,7	6	39,5	2,4	6	0.48
pCO2 (mmHg)	33,3	0,9	6	33,5	3,9	6	0.95
lactate (mmol/L)	3,1	0,3	6	3,4	0,5	6	0.68
pH	7,35	0,01	6	7,34	0,03	6	0.63
Shunt fraction
qs/Qt	0,074	0,014	6	0,072	0,011	6	0.95
PaO2/FiO2	555,6	16,9	6	523,7	40,74	6	0.48

^*p<0.05 vs. wild-type group.