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. 2020 Oct 20;19(11):e13253. doi: 10.1111/acel.13253

Table 2.

Proteins with robust absolute fold change >1.1 for longevity

Gene UniProt # Peptides Protein Name Meta Fold Change Meta p
C9 CO9 19 Complement component C9 −1.217 0.0002
S100A9 S10A9 3 Protein S100‐A9 −1.206 0.0700
CD163 C163A 5 Scavenger receptor cysteine‐rich type 1 protein M130 −1.179 0.0179
CRP CRP 6 C‐reactive protein −1.170 0.0183
IGHM IGHM 19 Immunoglobulin heavy constant mu −1.157 0.0002
C7 CO7 49 Complement component C7 −1.150 0.0001
FCGR3A FCG3A 4 Low affinity immunoglobulin gamma Fc region receptor III‐A −1.148 0.0984
LGALS3BP LG3BP 14 Galectin‐3‐binding protein −1.148 0.0002
NRP1 NRP1 3 Neuropilin‐1 −1.140 0.0966
ALCAM CD166 4 CD166 antigen −1.139 0.0535
GPLD1 PHLD 7 Phosphatidylinositol‐glycan‐specific phospholipase D −1.136 0.0239
B2 M B2MG 7 Beta‐2‐microglobulin −1.133 0.0133
A2 M A2MG 21 Alpha‐2‐macroglobulin −1.133 0.0002
MMP2 MMP2 5 72 kDa type IV collagenase −1.132 0.0286
VWF VWF 58 von Willebrand factor −1.120 0.0001
CSF1R CSF1R 5 Macrophage colony‐stimulating factor 1 receptor −1.119 0.0390
HPR HPTR 13 Haptoglobin‐related protein −1.117 0.0003
CFD CFAD 7 Complement factor D −1.111 0.0078
CD5L CD5L 6 CD5 antigen‐like −1.111 0.0788
FCGBP FCGBP 34 IgGFc‐binding protein −1.108 0.0001
IGHG3 IGHG3 13 Immunoglobulin heavy constant gamma 3 −1.106 0.0014
F2 THRB 53 Prothrombin −1.104 0.0001
CST3 CYTC 7 Cystatin‐C −1.102 0.0569
PTGDS PTGDS 4 Prostaglandin‐H2 D‐isomerase −1.101 0.0826
MCAM MUC18 7 Cell surface glycoprotein MUC18 −1.101 0.0445