MRI-T2W and PET images of [18F]DPA-714 in DPCPX, vehicle and ENBA-treated ischemic rats. MRI (T2W) (A, B) and TSPO receptor PET signal (C) images of axial planes at the level of the ischemic lesion. Infarct volume with MRI (T2W) (D, E), neurological score (F) were evaluated at day 1 after ischemia (before the start of treatments) and at day 7 after MCAO in DPCPX (n = 7), vehicle (n = 7) and ENBA-treated (n = 6) rats. [18F]DPA-714 PET signal was quantified at day 7 after ischemia (G). *p < 0.05 compared with vehicle; #p < 0.05, ##p < 0.01 and ##p < 0.001 compared with day 1; $p < 0.05, compared with MCAO+DPCPX; &p < 0.05 and &&p < 0.01 compared with MCAO+ENBA. Values are presented as scatter dot blot (mean ± SD).