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. 2021 Jan 1;11(1):346–360. doi: 10.7150/thno.48995

Figure 2.

Figure 2

ß-hydroxybutyrate plasma levels. (A). Higher levels of ß-hydroxybutyrate (ß-HB) were seen 70 days post injury in the new-KD fed animals compared to injured animals fed with control diet; In the craniotomy group ß-HB levels were not detectable (Unpaired t-test; ***p < 0.0009, F(8, 2) = 5.709). n=10/group. Lesion size. (B). Graph showing a significant reduction in lesion size in CCI mice treated with the new-KD compared with CCI-Control vs. craniotomy mice, at 70 days post-TBI (Unpaired t-test; p =0.01, F(5, 4) = 2.161; **p<0.01) and representative sections stained with H&E showing differences in lesion size. n=5/group. Oxidative stress. (C). Immunohistochemistry quantification of 8-OHG positive cells around the lesion border 70 days post-TBI (One-way ANOVA p<0.0001, F(3,15) = 227.8; Tukey's multiple comparisons test ***p <0.001), and representative images (a-c). n=5/group.