Figure 2.

Antitumor treatment study of ¹⁷⁷Lu-DOTA-Y003 and Y003 in MC38 tumor-bearing mice. A. Synthesis and radiolabeling of ¹⁷⁷Lu-DOTA-Y003. B-C. Treatment flow chart of Y003 (B) and ¹⁷⁷Lu-DOTA-Y003 (C). D. Tumor growth curve of Y003 immunotherapy. E. Survival curve of mice in the Y003 immunotherapy groups. F. Record of body weight in the Y003 immunotherapy groups. G. Tumor growth curve of the ¹⁷⁷Lu-DOTA-Y003 therapy groups. H. Survival curve of mice in the ¹⁷⁷Lu-DOTA-Y003 therapy groups. I. Record of body weight in the ¹⁷⁷Lu-DOTA-Y003 therapy groups (n = 7/group).