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. 2020 Nov 3;21(1):6. doi: 10.3892/ol.2020.12267

Figure 1.

Figure 1.

Higher TRIM59 mRNA expression in tumor tissues and cell lines. (A) TRIM59 mRNA levels in human tumor tissues and matched healthy tissues from 40 patients were determined via reverse transcription-quantitative PCR. The positive log2 value indicated higher expression levels of TRIM59 in human tumor tissues compared with matched healthy tissues. (B) TRIM59 mRNA levels in a hESC cell line and matched human esophageal epithelial cells. TRIM59 protein expression levels in human tumor tissues and matched healthy tissues were (C) determined via western blotting and (D) semi-quantified (n=112). TRIM59 protein expression levels in human tumor tissues and matched healthy tissues were (E) determined via immunofluorescence staining (scale bar, 50 µm) and (F) quantified. (G) Kaplan-Meier survival curve for patients with hESC. Higher TRIM59 expression levels were associated with poor patient survival. *P<0.05 and **P<0.01 vs. HEEC or healthy. TRIM59, tripartite motif 59; hESC, human esophageal cancer; HEEC, human esophageal epithelial cells.