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. 2020 Nov 3;21(1):6. doi: 10.3892/ol.2020.12267

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — TRIM59 knockdown regulates the expression levels of apoptosis- and migration-related proteins in response to cisplatin. (A) Bcl-2 mRNA expression levels (n=3). Bcl-2 protein expression levels were (B) determined via western blotting and (C) semi-quantified. (D) The mRNA expression levels of MMP2 and MMP9. MMP2 and MMP9 protein expression levels were (E) determined via western blotting and (F) semi-quantified. *P<0.05 and **P<0.01 vs. siNC. TRIM59, tripartite motif 59; MMP, matrix metallopeptidase; si, small interfering RNA; NC, negative control.