Table I.

Aberrant expression of TET proteins in various cancers.

Name of protein	Cancer types	Alteration	Consequent effects	(Refs.)
TET1	Breast cancer, colon cancer, liver cancer	Decreased expression	Advanced cancer stage, nodal metastases and poor overall survival	(64,72)
TET2	Leukemia, lymphoma	Mutation	Aberrant self-renewal and advanced-stage disease	(73–76)
TET3	Ovarian cancer	Increased expression	Unfavorable prognosis	(77)
TET3	Glioblastoma	Decreased expression	Promoted tumorigenesis	(78)

TETs, ten-eleven translocation family proteins.