Table 1.
Inflammatory molecules (cytokines, chemokines, angiogenic factors) upregulated in conditions of diabetic retinopathy.
| Analyzed tissue | Study cohort (n) | Inflammatory mediators | Reference |
|---|---|---|---|
| Vitreous humor | 60 | IL-6, IL-8, MCP-1, VEGF | (77) |
| Vitreous humor | 82 | IL-1β, IL6, IL8, CCL2, EDN1, VEGF, TNF-α | (78) |
| Vitreous humor & serum | 68 | IL-6, IL-8, TNF-α | (79) |
| Vitreous humor | 80 | IL-1β, IL-6, IL-8, CXCL-9, CXCL-10, TNF-α | (80) |
| Vitreous humor | 160 | IL-6, IL-8, IL-13, IP-10, MCP-1, MIP-1β, PDGF, VEGF | (81) |
| Vitreous humor | 21 | IL-1β, TNF-α | (6) |
| Vitreous humor | 50 | IL-1β, TNF-α, IL-6, IL-8 | (5) |
| Vitreous humor | 345 | IL-6, IL-8, MCP-1, | (82) |
| Aqueous humor | 61 | IL-1β, IL-2, IL-4, IL-5, IL-6, TNF-α, VEGF | (83) |
| Retinas of rats & human retinal endothelial cells | N/A | CCL2 | (84) |
| Retinal endothelial cells & vitreous humor | 69 | CCL2, CCL-4, CXCL-9, CXCL-10, MCP-1 | (85) |