. 2020 Nov 6;7:521078. doi: 10.3389/fmed.2020.521078

Table 3.

Univariate analysis between the change of corneal densitometry after refractive surgery and type of operation, age, SE, CCT, and planned ablation depth/lenticule thickness.

Variable	Postoperative month 6–12										Postoperative year 5
	Group^†		Age		SE		CCT		LT/AD		Group^†		Age		SE		CCT		LT/AD
	Coef	P	Coef	P	Coef	P	Coef	P	Coef	P	Coef	P	Coef	P	Coef	P	Coef	P	Coef	P
ANTERIOR LAYER
0–2 mm	−1.012	0.54	0.048	0.74	0.263	0.77	0.011	0.61	−0.026	0.28	−3.043	0.01^*	0.022	0.83	1.785	0.14	0.007	0.78	0.023	0.50
2–6 mm	−0.481	0.74	0.038	0.76	0.643	0.50	0.012	0.56	−0.025	0.30	−2.659	0.02^*	0.008	0.93	1.753	0.11	0.007	0.74	0.021	0.50
6–10 mm	−0.58	0.64	−0.002	0.98	0.256	0.84	0.012	0.53	−0.035	0.20	−2.252	0.04^*	0.021	0.81	0.98	0.34	0.022	0.31	0.004	0.89
CENTRAL LAYER
0–2 mm	−0.995	0.26	0.028	0.71	−0.037	0.94	0.004	0.75	−0.013	0.36	−1.903	0.007^*	−0.011	0.85	1.196	0.11	0.006	0.67	0.026	0.18
2–6 mm	−0.449	0.52	0.034	0.58	0.109	0.82	0.005	0.60	−0.01	0.48	−1.494	0.02^*	−0.007	0.89	0.937	0.16	0.005	0.71	0.026	0.14
6–10 mm	−0.35	0.59	−0.002	0.98	−0.182	0.77	0.006	0.55	−0.011	0.45	−1.347	0.03^*	−0.002	0.97	0.774	0.22	0.01	0.40	0.02	0.25
POSTERIOR LAYER
0–2 mm	−0.764	0.40	0.012	0.88	−0.182	0.71	0.004	0.77	−0.016	0.31	−1.138	0.16	0.001	0.99	0.802	0.28	0.02	0.21	0	1.00
2–6 mm	−0.255	0.74	0.024	0.72	0.161	0.72	0.005	0.68	−0.013	0.36	−1.102	0.12	−0.005	0.93	0.814	0.23	0.015	0.27	0.008	0.65
6–10 mm	−0.124	0.86	0.042	0.50	−0.028	0.97	0.004	0.75	−0.011	0.51	−1.408	0.03^*	−0.001	0.98	0.9	0.15	0.013	0.29	0.016	0.36
TOTAL THICKNESS
0–2 mm	−0.899	0.42	0.032	0.74	0.01	0.99	0.006	0.69	−0.019	0.29	−2.013	0.01^*	0.007	0.92	1.291	0.13	0.009	0.57	0.015	0.52
2–6 mm	−0.391	0.68	0.031	0.71	0.293	0.64	0.007	0.62	−0.017	0.34	−1.737	0.02^*	−0.001	0.98	1.18	0.13	0.008	0.61	0.018	0.40
6–10 mm	−0.361	0.66	0.014	0.85	0.001	0.99	0.007	0.58	−0.019	0.33	−1.664	0.02^*	0.007	0.91	0.898	0.22	0.014	0.33	0.012	0.55

P < 0.05.

^†

SMILE, 0; FS-LASIK, 1.

CCT, central corneal thickness; SE, spherical equivalent; LT, lenticule thickness; AD, ablation depth; Coef, univariate coefficient.