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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Neuroscience. 2020 Jan 23;443:188–205. doi: 10.1016/j.neuroscience.2020.01.020

Figure 5:

Figure 5:

ICV CCL2 administration (1 μg/μl, E14) compared to ICV Control and No-ICV Control groups (n = 7/sex/group) stimulates in the LH of E19 embryos the expression of CCL2, CCR2, and MCH measured using qRT-PCR, with the data presented here as mRNA fold change (compared to No-ICV Control) based on average ratio scores given in Table 5. This stimulatory effect on CCL2, CCR2, and MCH mRNA levels is evident in both the female and male embryos but is significantly greater in the female embryos. Abbreviations: CCL2, C-C motif ligand 2; MCH, melanin-concentrating hormone; LH, lateral hypothalamus. Data are mean ± SEM. *p < 0.05 versus control group. #, p < 0.05 versus males.