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. 2020 Nov 19;2(6):e200406. doi: 10.1148/ryct.2020200406

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(a) Radiologic-pathologic correlation in patient 4, an 81-year-old woman. Gross specimen shows congestion, interlobular septal edema, and emphysema (arrow). CT scan reveals consolidation (arrow) in the posterior parts of the left lower lobe and crazy paving (arrowhead) in the apical upper lobe. Photomicrograph reveals both hyaline membranes as correlates of acute exudative (arrowheads) and intra-alveolar fibrohistiocytic proliferates as signs of proliferative diffuse alveolar damage (DAD) (arrows). (Hematoxylin-eosin [H&E] stain, magnification not available [N/A].) (b) Radiologic-pathologic correlation in patient 6, a 71-year-old man. Gross specimen shows congestion and severe consolidation (arrow). CT scan shows obstruction and consolidation in the posterior parts of the upper and lower right lobe (arrow). Photomicrograph shows extensive bronchopneumonia, dilated capillaries (arrows), vasculitis (insert at bottom right), and microthrombosis (not shown). Next-generation sequencing identified bacterial species such as Staphylococcus aureus and several strains of streptococcal species. (H&E stain, magnification N/A.) (c) Radiologic-pathologic correlation in patient 9, a 58-year-old man. Gross specimen shows congestion, interlobular septal edema, and multiple thromboembolisms (insert at lower left). CT scan reveals subtotal consolidation of the left lower lobe (arrow) and bilateral pulmonary embolisms (not shown). Photomicrograph shows hyaline membranes as correlates of acute exudative (arrows) and fibroblastic proliferations as signs of proliferative DAD (arrowhead), as well as alveolar hemorrhage (far right). (H&E stain, magnification N/A.) — (a) Radiologic-pathologic correlation in patient 4, an 81-year-old woman. Gross specimen shows congestion, interlobular septal edema, and emphysema (arrow). CT scan reveals consolidation (arrow) in the posterior parts of the left lower lobe and crazy paving (arrowhead) in the apical upper lobe. Photomicrograph reveals both hyaline membranes as correlates of acute exudative (arrowheads) and intra-alveolar fibrohistiocytic proliferates as signs of proliferative diffuse alveolar damage (DAD) (arrows). (Hematoxylin-eosin [H&E] stain, magnification not available [N/A].) (b) Radiologic-pathologic correlation in patient 6, a 71-year-old man. Gross specimen shows congestion and severe consolidation (arrow). CT scan shows obstruction and consolidation in the posterior parts of the upper and lower right lobe (arrow). Photomicrograph shows extensive bronchopneumonia, dilated capillaries (arrows), vasculitis (insert at bottom right), and microthrombosis (not shown). Next-generation sequencing identified bacterial species such as Staphylococcus aureus and several strains of streptococcal species. (H&E stain, magnification N/A.) (c) Radiologic-pathologic correlation in patient 9, a 58-year-old man. Gross specimen shows congestion, interlobular septal edema, and multiple thromboembolisms (insert at lower left). CT scan reveals subtotal consolidation of the left lower lobe (arrow) and bilateral pulmonary embolisms (not shown). Photomicrograph shows hyaline membranes as correlates of acute exudative (arrows) and fibroblastic proliferations as signs of proliferative DAD (arrowhead), as well as alveolar hemorrhage (far right). (H&E stain, magnification N/A.)