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. 2020 Nov 23;21:951. doi: 10.1186/s13063-020-04852-8

Table 3.

Traditional Chinese medicine (TCM) symptom assessment survey and evaluation standard

Signs/symptoms Score Scores
Normal: 0 Mild: 2 Moderate: 4 Severe: 6
Primary signs/symptoms Dry mouth and throat None Decreased saliva production Moderate thirst relieved by drinking fluids Severe thirst with constant need to drink fluids
Fatigue None Cannot sustain heavy work Can manage mild intensity work Can only perform daily activities
Secondary signs/symptoms Prone to be hungry and eat more None Easy to be hungry Easy to be hungry and unbearable hunger Unbearable hunger and hypoglycemia
Shortness of breath None Shortness of breath after mild activity Shortness of breath after moderate activity Unable to talk or catch breath even without activity
Heat sensation in chest, palms, and soles None Heat sensation in palms and soles at night Moderate heat sensation in chest, palms and soles Severe heat sensation in chest, palms, and soles and desire to expose body
Fixed pain in the chest, lower back, or limbs None Occasional and relieved spontaneously within half an hour Less than three hours a day, relieved by common drugs Continuously fixed pain, relieved only by painkillers
Numbness of the limbs None Tips of hands and feet Hands and feet Limbs
Tongue and pulse Tongue Dark red tongue with less fluid coating; others (description):
Pulse Weak and thin pulse; others (description):

Manifestation of tongue and pulse is only for reference without being calculated in the scores

Evaluation standard of total effective rate of TCM syndrome scale score

(1) Clinical recovery: the clinical symptoms and signs disappear or basically disappear, and syndrome scores are reduced by ≥ 95%

(2) Significantly effective: the clinical symptoms and signs are significantly improved, and syndrome scores are reduced by ≥ 70%

(3) Effective: the clinical symptoms and signs are improved, and syndrome scores are reduced by ≥ 30%

(4) Invalid: the clinical symptoms and signs are not improved, or even worsened, and syndrome scores are reduced by less than 30%

The calculation formula (Nimodipine method) is as follows: [(scores before treatment − scores after treatment) ÷ scores before treatment] × 100%

Total effective rate = (clinical recovery + significantly effective + effective) number of cases/total number of cases × 100%

The total effective rate of the KLX group and the control group after treatment is calculated and compared