TABLE 3.
Associations between antimicrobial resistance phenotype and antimicrobial resistance gene (ARG) presence in Mannheimia haemolytica (MH) and Pasteurella multocida (PM) isolates collected post-mortem from bovine respiratory disease mortalities.
| Resistance phenotype/ARG | No. isolates with resistance phenotype MH| PM | % of the resistant isolates with ARGa MH| PM | % of the susceptible isolates with ARG MH| PM |
| AMP/blaOXA–2 | 15 | 10 | 54 | 10 | 12.9 | 0 |
| PEN/blaOXA–2 | 15 | 6 | 53.4 | 16.7 | 12.9 | 0 |
| XNL/blaOXA–2 | 2 | 9 | 0 | 11.2 | 17.3 | 0 |
| CTET/tet(H) | 21 | 20 | 90.5 | 85 | 85 | 72 |
| OXYT/tet(H) | 131 | 61 | 96.2* | 86.9 | 0 | 0 |
| FFN/floR | 21 | 0 | 100** | 0 | 0 | 0 |
| SDM/sul2 | 146 | 70 | 79.5 | 62.9 | 0 | 0 |
| SXT/sul2 | 112 | 59 | 83.1 | 67.8 | 65.8 | 36.4 |
| SPE/aadA25 | 32 | 44 | 90.7** | 2.3 | 0 | 0 |
| SPE/aadB | 32 | 44 | 78.2* | 2.3 | 0 | 0 |
| NEO/strA | 120 | 49 | 96.7** | 85.8* | 0 | 9.6 |
| NEO/strB | 120 | 49 | 96.7** | 85.8* | 0 | 4.8 |
| NEO/aphA1 | 120 | 49 | 96.7** | 85.8* | 0 | 4.8 |
| GENT/strA | 30 | 3 | 70 | 33.4 | 81.2 | 64.2 |
| GENT/strB | 30 | 3 | 70 | 33.4 | 81.2 | 62.7 |
| GENT/ aphA1 | 30 | 3 | 70 | 33.4 | 81.2 | 62.7 |
| GENT/aadB | 30 | 3 | 83.4* | 33.4 | 0 | 0 |
| GENT/aadA25 | 30 | 3 | 96.7** | 33.4 | 0 | 0 |
| TUL/msr(E) | 92 | 49 | 33.7 | 4.1 | 3.7 | 4.8 |
| TUL/mph(E) | 92 | 49 | 33.7 | 4.1 | 3.7 | 4.8 |
| TUL erm(42) | 92 | 49 | 22.9 | 8.2 | 1.9 | 47.7 |
| TIL/msr(E) | 97 | 62 | 29.9 | 4.9 | 8 | 0 |
| TIL/mph(E) | 97 | 62 | 29.9 | 4.9 | 8 | 0 |
| TIL/erm(42) | 97 | 62 | 22.7 | 22.6 | 0 | 0 |
| TYLT/msr(E) | 147 | 64 | 22.5 | 4.7 | 0 | 0 |
| TYLT/mph(E) | 147 | 64 | 22.5 | 4.7 | 0 | 0 |
| TYLT/erm(42) | 147 | 64 | 15 | 21.9 | 0 | 0 |
| CLIND/msr(E) | 57 | 70 | 42.2 | 4.3 | 10 | 0 |
| CLIND/mph(E) | 57 | 70 | 42.2 | 4.3 | 10 | 0 |
| CLIND/erm(42) | 57 | 70 | 38.6 | 20 | 0 | 0 |
a Based on significant (P < 0.05) Pearson’s correlation coefficient; *r > 0.8, **r > 0.9.