Table 2.
Cohort split into EpCAM classification groups. Group differences assessed by Fisher’s Exact test for categorical variables and Kruskal-Wallis-test for numerical variables
| Baseline Characteristics | EpCAM-negative n = 29 (42.1%) | EpCAM- heterogeneous n = 33 (47.8%) | EpCAM- homogeneous n = 7 (10.1%) | p-value |
|---|---|---|---|---|
| Sex | ||||
| m | 24 (77.42) | 26 (78.79) | 5 (71.43) | 0.920 |
| f | 7 (22.58) | 7 (21.21) | 2 (28.57) | |
| Age at surgical procedure (years) | ||||
| range | 38–84 | 18–81 | 58–76 | 0.326 |
| median (n) | 69 (29) | 66 (33) | 63 (7) | |
| ECOG | ||||
| 0 | 17 (58.62) | 18 (56.25) | 2 (33.33) | 0.535 |
| 1 | 11 (37.93) | 14 (43.75) | 4 (66.67) | |
| 2 | 1 (3.45) | 0 (0) | 0 (0) | |
| BCLC | ||||
| A | 19 (70.37) | 18 (64.29) | 2 (33.33) | 0.152 |
| B | 8 (29.63) | 7 (25) | 3 (50) | |
| C | 0 (0) | 3 (10.71) | 1 (16.67) | |
| Histological Stage of Liver | ||||
| No Fibrosis | 6 (22.22) | 6 (21.43) | 3 (42.86) | 0.808 |
| Fibrosis | 10 (37.04) | 9 (32.14) | 2 (28.57) | |
| Cirrhosis | 11 (40.74) | 13 (46.43) | 2 (28.57) | |
| Child Pugh Stage | ||||
| A | 11 (100) | 11 (84.62) | 1 (50) | 0.111 |
| B | 0 (0) | 2 (15.38) | 1 (50) | |
| Aetiology | ||||
| Alcohol | 9 (24.32) | 11 (29.73) | 2 (20) | 0.617 |
| HBV | 7 (18.92) | 4 (10.81) | 2 (20) | |
| HCV | 9 (24.32) | 5 (13.51) | 1 (10) | |
| NASH | 4 (10.81) | 7 (18.92) | 0 (0) | |
| Other | 4 (10.81) | 3 (8.11) | 2 (20) | |
| w/o liver disease | 4 (10.81) | 7 (18.92) | 3 (30) | |
| Bilirubin | ||||
| range | 0.3–1.7 | 0.3–2.3 | 0.4–0.7 | 0.105 |
| median (n) | 0.65 (22) | 0.5 (25) | 0.5 (7) | |
| Albumin | ||||
| range | 31–43 | 2.34–43 | 30–42 | 0.152 |
| median (n) | 38 (20) | 36 (21) | 35 (6) | |
| INR | ||||
| range | 0.93–2.42 | 0.92–3.08 | 0.95–1.25 | 0.863 |
| median (n) | 1.06 (25) | 1.055 (24) | 1.06 (6) | |