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. 2020 Nov 18;26:e926323-1–e926323-11. doi: 10.12659/MSM.926323

Figure 2.

Figure 2

Effects of t-PA, proBDNF, or NS administered by ICV injection on depression-like behavior in PSD models rats. Histograms show (A) body weight (feeding behavior), (B) sucrose preference, (C) rearing activity, and (D) locomotor activity in rats injected with NS, t-PA, or proBDNF as indicated. N=8 rats/group. * P<0.05 versus NS-treated rats; # P<0.05 versus t-PA-treated rats. BDNF – brain-derived neurotrophic factor; ICV – intracerebroventricular; NS – normal saline; PSD – poststroke depression; t-PA – tissue plasminogen activator.