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. 2020 Nov 18;26:e926323-1–e926323-11. doi: 10.12659/MSM.926323

Figure 7.

Figure 7

Effects of t-PA, proBDNF, and NS ICV injection on microglial expression of BDNF or TrkB in the amygdala 1 week after injection. (A) BDNF or TrkB expression (red fluorescence) in CD11b-positive microglia (green fluorescence) (bar=20 μm). (B) Histograms show the number of BDNF/CD11b- or TrkB/CD11b-positive cells in microglia of PSD model rats 1 week after ICV injection. N=5 rats/group. * P<0.05 versus NS injection; # p<0.05 versus tPA injection. BDNF – brain-derived neurotrophic factor; ICV – intracerebroventricular; NS – normal saline; PSD – poststroke depression; t-PA – tissue plasminogen activator; TrkB – tyrosine kinase receptor B.