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. 2020 Nov 19;10(4):2045894020913475. doi: 10.1177/2045894020913475

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© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 1. — The renin–angiotensin–aldosterone pathway regulates blood pressure and electrolyte balance in the body.

ACE: angiotensin-1 converting enzyme; AGTR1: angiotensin II receptor; SF1: steroidogenic transcription factor.

Note: Hash (#) represents HAPE-associated genetic variants.