Table 2.
Comparison of patients whose RP contained any foci of ductal carcinoma (PDA) with those with pure acinar adenocarcinoma (PAA)
| Grade Group, CI 95%, P Value | PDA (n = 128) | PAA (n = 901) | P Value | |
|---|---|---|---|---|
| Age, mean, years (range) | GG2-GG5 | 64.9 (40–85) | 62.5 (40–85) | <.001 |
| GG2 | 63.4 | 61.2 | .21 | |
| GG3 | 64.9 | 63.6 | .39 | |
| GG4–5 | 65.6 | 64.6 | .41 | |
| PSA, ng/ml (range) | GG2-GG5 | 11.6 (1–106) | 9.7 (.3–181.9) | .1 |
| PSAD, gn/ml/gr | GG2-GG5 | 0.25 (.03–1.31) | .22 (.1–3.12) | .2 |
| Extensive bilateral disease (%) | GG2-GG5, | 20/128 (15.6%) | 54/901 (6%) | <.001 |
| GG2 | 2/21 (9.5%) | 13/473 (2.8%) | .13 | |
| GG3 | 5/37 (13.5%) | 12/174 (6.9%) | .18 | |
| GG4–5 | 13/70 (18.6%) | 29/254 (11.4%) | .16 | |
| Regional lymph lode metastasis | GG2-GG5 | 8/127 (6.3%) | 24/900 (2.7%) | .049 |
| GG2 | 0/21 | 0/472 | N/A | |
| GG3 | 4/37 (11.1%) | 6/174(3.4%) | .73 | |
| GG4–5 | 4/70 (5.7%) | 17/254 (6.7%) | 1.0 | |
| Grade group distribution | GG2 | 21 (16.4%) | 473 (52.5) | <.001 |
| GG3 | 37 (28.9%) | 174 (19.3%) | ||
| GG4 | 7 (5.5%) | 29 (3.2%) | ||
| GG5 | 63 (49.2%) | 225 (25.0%) | ||
| Prostate weight, mean, grams (range) | GG2-GG5 (range) | 51.5 (19–171) | 48.1 (13.5–260) | .14 |
| Number of tumor nodules, mean (range) | GG2-GG5(range) | 2.6 (1–6) | 2.7 (1–7) | .09 |
PSA, prostate-specific antigen; PSAD, PSA density; RP, radical prostatectomy; SD, standard deviation.