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. 2020 Nov 23;150:104641. doi: 10.1016/j.micpath.2020.104641

Fig. 4.

Fig. 4

SARS-CoV-2 nsp15 evolutionary changes in compared to other human coronaviruses. (a) Phylogenetic tree construction by the neighbour joining method was performed using MEGA X software, with bootstrap values being calculated from 1000 trees using amino acid sequences of nsp15, (b) Pairwise identity % plot of nsp15 CoVs amino acid sequences performed using SDT program, (c) 3D crystal structure and (d) the multiple amino acid sequence alignment for of the nsp15 of SARS-CoV-2 (PDB ID: 6VWW) compared to other human coronaviruses.