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. 2020 Nov 23;33(1):65–77.e2. doi: 10.1016/j.cmet.2020.11.014

Table 3.

Comparison of Treatment of Patients between the Insulin and Non-insulin Groups

All Patients (n = 689) Unmatched
PSM (1:1)
Insulin (n = 346) Non-insulin (n = 343) SMD p Insulin (n = 183) Non-insulin (n = 183) SMD p
Antidiabetic treatment, n (%): metformin 223 (32.4) 91 (26.3) 132 (38.5) 0.263 <0.001 51 (27.9) 78 (42.6) 0.313 0.003
Antidiabetic treatment, n (%): α-glucosidase inhibitors 295 (42.8) 141 (40.8) 154 (44.9) 0.084 0.271 79 (43.2) 79 (43.2) <0.001 >0.999
Antidiabetic treatment, n (%): sulfonylureas 109 (15.8) 32 (9.2) 77 (22.4) 0.368 <0.001 14 (7.7) 40 (21.9) 0.409 <0.001
Antidiabetic treatment, n (%): dipeptidyl peptidase-4 inhibitors 50 (7.3) 23 (6.6) 27 (7.9) 0.047 0.536 16 (8.7) 15 (8.2) 0.020 0.851
Antidiabetic treatment, n (%): insulin-sensitizing agents 15 (2.2) 4 (1.2) 11 (3.2) 0.141 0.065 2 (1.1) 4 (2.2) 0.086 0.410
Antiviral treatment, n (%) 287 (41.7) 147 (42.5) 140 (40.8) 0.034 0.657 84 (45.9) 86 (47.0) 0.022 0.834
Antibacterial treatment, n (%) 492 (71.4) 267 (77.2) 225 (65.6) 0.258 <0.001 124 (67.8) 129 (70.5) 0.059 0.572
Glucocorticoids, n (%) 266 (38.6) 182 (52.6) 84 (24.5) 0.603 <0.001 81 (44.3) 55 (30.1) 0.297 0.005
Oxygen therapy, no. (%) 550 (79.8) 299 (86.4) 251 (73.2) 0.334 <0.001 155 (84.7) 142 (77.6) 0.182 0.082