Table 2.

Response to immunotherapy based on pretreatment BMI trend

Outcome	Any decrease (n=308)	No decrease (n=321)	P value
Best overall response—no. (%)			0.04
Complete response (CR)	31 (10.1)	37 (11.5)
Partial response (PR)	54 (17.5)	85 (26.5)
Stable disease (SD)	56 (18.2)	58 (18.1)
Progressive disease (PD)	162 (52.6)	135 (42.1)
Could not be evaluated	5 (1.6)	6 (1.9)
Objective response rate*			0.01
No. (%)	85 (27.6)	122 (38.0)
95% CI†	22.7 to 33.0	32.7 to 43.6
Disease control rate‡			0.01
No. (%)	141 (45.8)	180 (56.1)
95% CI†	40.1 to 51.5	50.1 to 61.6

*Objective response rate was defined as the percentage of patients who had CR or PR.

†The 95% CIs were calculated using the Clopper-Pearson method.

‡Disease control rate was defined as the percentage of patients who had CR, PR or SD