Figure S3.

Bulk PBMCs Return to Immune Quiescence by Visit 1, Related to Figure 1

(A and B) Representative flow cytometry plots and frequencies of αβ and γδ T cell subsets at Visit 1 (V1) in PBMCs from healthy control (HC) and SARS-CoV-2-recovered (CoV2⁺) individuals.

(C and D) Representative flow cytometry plots and frequencies of CD4⁺ and CD8⁺ T cell effector/activation states (Ki67⁺, T-bet⁺, HLA-DR⁺CD38⁺) of total non-naive, memory CD45RA⁺CCR7^+/− CD4⁺ or CD8⁺ T cells at V1 in HC and CoV2⁺ PBMCs.

(E and F) Representative flow cytometry plots and frequencies of CD4⁺ memory and T-helper subsets at V1 in HC and CoV2⁺ PBMCs.

(G and H) Representative flow cytometry plots and frequencies of cTfh (CXCR5⁺CD45RA^-) and cTfh activation (ICOS⁺PD-1⁺) and helper (CXCR3^+/−CCR6^+/−) subsets at V1 in HC and CoV2⁺ PBMCs.

(I) Frequency of B cells (CD19⁺CD3^-) at V1 in HC and CoV2⁺ PBMCs.

Statistics determined by two-tailed Mann-Whitney tests. Multiple testing correction significance cutoff at FDR = 0.05 is p value < 0.05. Error bars represent mean and SD. Data from two experiments.