Table 1.
Summary of all included eligible studies.
| First author | Year | Country | No. of patients | Tumor type | Method | Cut-off | Outcome | Analysis | NOS |
|---|---|---|---|---|---|---|---|---|---|
| Zhang (18) | 2017 | China | 1,117 | Breast cancer | IHC | NR | OS | Kaplan-Meier curves | 7 |
| Wang (17) | 2018 | China | 140 | Breast cancer | IHC | NR | OS/DFS | Multivariate | 7 |
| Parris | 2013 | Sweden | 63 | Breast cancer | IHC | IHC ≥1+ | DFS | Kaplan-Meier curves | 8 |
| Parris (16, 20) | 2014 | Sweden | 43 | OSCC | IHC | IHC ≥1+ | OS | Multivariate | 7 |
| Mukhtar (15) | 2012 | America | 116 | Breast cancer | IHC | NR | RFS | Kaplan-Meier curves | 8 |
| McKiernan (13) | 2011 | Ireland | 295 | Breast cancer | RT-PCR | NR | OS/DFS | Univariate | 8 |
| Yun | 2014 | Korea | 69 | Prostate cancer | IHC | IHC ≥1+ | RFS | Multivariate | 8 |
| Ha (23) | 2010 | Korea | 103 | NMIBC | RT-PCR | 171.2 × 103 copies/μl | PFS | Multivariate | 9 |
| Minami (26) | 2010 | Japan | 77 | Bladder cancer | IHC | IHC score ≥2 | RFS | Multivariate | 8 |
| Miller (14) | 2017 | America | 417 | Breast cancer | AQUA | AQUA score >95.27 | OS/DFS | Multivariate | 8 |
| Nicklas (27) | 2018 | Austria | 158 | NMIBC | IHC | IHC ≥1+ | RFS/PFS | Multivariate | 8 |
| Koh | 2018 | Korea | 94 | NSCCL | IHC | IHC ≥1+ | DFS | Kaplan-Meier curves | 8 |
| Fan (30) | 2012 | China | 125 | Gastric cancer | IHC | Positive cells ≥64 | OS | Kaplan-Meier curves | 8 |
IHC, Immunohistochemistry; AQUA, automated quantitative immunofluorescence; RT-PCR, reverse transcriptase polymerase chain reaction; OS, Overall survival; DFS, Disease-free survival; PFS, Progression-free survival; RFS, Recurrent-free survival; NR, Not reported; NOS, Newcastle-Ottawa Scale; OSCC, oral squamous cell carcinoma; NMIBC, non-muscle invasive bladder cancer; NSCCL, non-small cell carcinoma of the lung.