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. Author manuscript; available in PMC: 2020 Nov 23.
Published in final edited form as: Front Ecol Evol. 2019 Jul 12;7:256. doi: 10.3389/fevo.2019.00256

FIGURE 2 |.

FIGURE 2 |

Neprilysins (M13 peptidases) identified in Physocyclus mexicanus venom are homologs of neprilysins from diverse organisms. (A) An alignment of the region of the conserved active sites of neprilysins with conserved binding sites labeled based on Sterchi et al. (2008). Sequence names are color coded by taxonomic source groups. (B) A Bayesian phylogeny of neprilysins with branches color coded by source group. Branch width correlates with posterior probability support for that branch. Names of taxa are in color when they have been confirmed to be in venom proteomes. The label ∧ indicates that sequence was identified in a venom gland EST.