Fig. 2.

The features of the Hemagglutinin protein of the H5N1 influenza virus. The conserved regions of HA proteins with their sequences and positions have been shown. There are 9 regions including a 24 amino acid, and a 30 amino acid region (blue colored sequences) found to be 100% conserved in the HA-2 domain of Hemagglutinin sequences in Bangladeshi H5 isolates (N = 220) circulating from 2007 to 2018. The B-cell epitope (GAIAGFIEGGWQGM) and the T-cell epitope (DVWTYNAELLVLMEN) selected are finally shown in a bold font. The signal peptide (green) is located at the N-terminal and the transmembrane region (red) is located at the C-terminal of the protein