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. 2020 Oct 6;95(14):e1963–e1970. doi: 10.1212/WNL.0000000000010463

Figure 1. Causal relationships between AD and sleep-related phenotypes in scatterplots (findings adjusted for multiple comparisons).

Figure 1

(A) Alzheimer disease (AD) → chronotype; (B) AD → insomnia; (C) AD → self-reported sleep duration; (D) AD → self-reported long sleep; (E) AD → accelerometer-based sleep duration; (F) AD → least active 5 hours (L5) timing; (G) AD → number of sleep episodes (APOE single nucleotide polymorphisms [SNPs] [rs7412 and rs429358] are labeled in red). MR = Mendelian randomization.