Fig 6. Non-invasive measurement of cutaneous wound tissue elastic-stiffness in adult mice.

Ultrasound imaging of adult murine normal skin and stented wounds tissue for the analysis of biomechanical property of db/+ mice (blue) and db/db mice (red). (a) Strain curves showing changes in wound edge tissue at 0, 3, 7, 10, and 14d post-wounding of db/+ mice and db/db mice. (b) Quantification of strains of normal skin (dotted lines, n = 3), wound edge of db/db and control db/+ mice post-wounding. Data represented as the mean ± SE, *p< 0.05, n = 6. (c) Strain curves showing changes in wound bed tissue at 0, 3, 7, 10, and 14d post-wounding of db/+ mice and db/db mice. (d) Quantification of normal skin (dotted lines, n = 3), wound bed strain of db/db and control db/+ mice post-wounding. Data represented as the mean ± SE, *p< 0.05, n = 6.