Table 3. Classification of catalog SNPs for alternate summary statistics.
Median Measurement | First Available Measurement | Maximum Measurement | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Lab | Testable Catalog SNPs | Concordant Increased Significance | Concordant Decreased Significance | Discordant Effect | Concordant Increased Significance | Concordant Decreased Significance | Discordant Effect | Concordant Increased Significance | Concordant Decreased Significance | Discordant Effect |
Chol | 91 | 0 | 12 | 0 | 1 | 11 | 1 | 2 | 4 | 6 |
Create | 36 | 2 | 0 | 0 | 2 | 2 | 1 | 0 | 8 | 1 |
EoAB | 31 | 0 | 6 | 0 | 0 | 9 | 0 | 0 | 2 | 1 |
EoRE | 28 | 0 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 1 |
HCT | 36 | 0 | 0 | 0 | 4 | 0 | 1 | 15 | 0 | 1 |
HDL | 101 | 0 | 6 | 3 | 0 | 15 | 1 | 0 | 27 | 5 |
Hgb | 34 | 0 | 0 | 0 | 5 | 0 | 0 | 12 | 0 | 0 |
LDL | 84 | 0 | 9 | 1 | 0 | 9 | 4 | 2 | 2 | 6 |
LymphAB | 35 | 0 | 0 | 0 | 0 | 3 | 1 | 5 | 1 | 2 |
LymphRE | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MCHC | 20 | 0 | 1 | 0 | 2 | 5 | 3 | 2 | 5 | 1 |
MCH | 64 | 0 | 16 | 27 | 0 | 33 | 8 | 0 | 33 | 7 |
MCV | 77 | 1 | 5 | 7 | 0 | 19 | 13 | 0 | 30 | 6 |
MonoAB | 43 | 2 | 3 | 0 | 0 | 9 | 0 | 0 | 13 | 1 |
MPV | 84 | 0 | 11 | 9 | 0 | 39 | 9 | 5 | 20 | 17 |
PLT | 102 | 0 | 0 | 1 | 7 | 7 | 1 | 0 | 19 | 5 |
PMNAB | 35 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 3 | 1 |
PMNRE | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
RBC | 50 | 0 | 4 | 4 | 13 | 0 | 1 | 21 | 0 | 0 |
RDW | 29 | 0 | 1 | 2 | 0 | 1 | 4 | 0 | 7 | 0 |
Trigs | 73 | 0 | 7 | 0 | 1 | 15 | 1 | 0 | 22 | 0 |
WBC | 33 | 0 | 4 | 5 | 0 | 7 | 1 | 0 | 9 | 0 |
Total | 1127 | 5 (0.4%) | 86 (7.6%) | 59 (5.2%) | 35 (3.1%) | 190 (16.9%) | 51 (4.5%) | 64 (5.6%) | 206 (18.3%) | 62 (5.5%) |