Table 1.

Clinicopathologic characteristics of the patient cohort

Characteristic	Overall, No. (%) (n = 52)	Standard Care, No. (%) (n = 27)	LS-HIPEC, No. (%) (n = 25)	p
Age, mean (SD)	61 (11)	64 (10)	57±10	0.02
Gender, male	35 (67.3)	17 (63)	18 (72)	0.48
Race/ethnicity
White	28 (53.8)	13 (48.1)	15 (60)	0.24
Black	5 (9.6)	2 (7.4)	3 (12)
Hispanic	9 (17.3)	7 (25.9)	2 (8)
Asian	8 (15.4)	3 (11.1)	5 (20)
Unknown	2 (3.8)	2 (7.4)	0 (0)
Tumor location
GEJ	19 (36.5)	10 (37)	9 (36)	0.73
Fundus/cardia	4 (7.7)	1 (3.7)	3 (12)
Body/antrum	20 (38.5)	11 (40.7)	9 (36)
Total stomach	9 (17.3)	5 (18.5)	4 (16)
Tumor grade
Moderate	9 (17.3)	4 (14.8)	5 (20)	0.62
Poor/undifferentiated	43 (82.7)	23 (85.2)	20 (80)
Signet ring cells	33 (64.7)	18 (66.7)	15 (62.5)	0.76
Linitis plastica	14 (32.6)	7 (31.8)	7 (33.3)	0.96
Clinical T stage
cT2	7 (18.9)	2 (10)	5 (29.4)	0.03
cT3	27 (73.0)	18 (90)	9 (52.9)
cT4	3 (8.1)	0 (0)	3 (17.6)
Clinical N stage
cN0	19 (55.9)	13 (68.4)	6 (40)	0.22
cN1	9 (26.5)	3 (15.8)	6 (40)
cN2	5 (14.7)	3 (15.8)	2 (13.3)
cN3	1 (2.9)	0 (0)	1 (6.7)
LS gross positive	34 (65.4)	17 (63)	17 (68)	0.70
LS-positive cytology only	18 (34.6)	10 (37)	8 (32)	0.70
PCI, median (range)	1.0 (0-6)	0.5 (0-6)	1.0 (0-4)	0.99
Affected regions, median (range)	1.0 (0-6)	1.0 (0-6)	1.0 (0-4)	0.74
Additional therapy
Chemo only	26 (50.0)	17 (63.0)	9 (36.0)	0.10
Chemoradiation/XRT	26 (50.0)	10 (37.0)	16 (64.0)
Response to therapy
Stable	12 (23.5)	8 (30.7)	4 (16.0)	0.48
Partial Response	33 (64.7)	15 (57.7)	18 (72.0)
Complete Radiologic Response	6 (11.8)	3 (11.5)	3 (12.0)

Abbreviations: GEJ, gastroesophageal junction; PCI, peritoneal carcinomatosis index; LS, laparoscopy; XRT, radiation