Table 3.
Comparison of incidence and hazard ratio of hyperlipidemia stratified by sex, age, and comorbidity between patients with and without gout.
| Variable | Gout | Crude HR (95% CI) | Adjusted HR† (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|
| No | Yes | |||||||
| Event | PY | Rate# | Event | PY | Rate# | |||
| All | 24485 | 1378799 | 17.8 | 13639 | 293172 | 46.5 | 2.61 (2.55, 2.66)∗∗∗ | 2.55 (2.50, 2.61)∗∗∗ |
| Sex | ||||||||
| Female | 7080 | 282065 | 25.1 | 3217 | 59166 | 54.4 | 2.14 (2.06, 2.23)∗∗∗ | 2.15 (2.06, 2.24)∗∗∗ |
| Male | 17405 | 1096734 | 15.9 | 10422 | 234006 | 44.5 | 2.80 (2.73, 2.87)∗∗∗ | 2.70 (2.64, 2.77)∗∗∗ |
| Stratified age | ||||||||
| ≤49 | 10087 | 850974 | 11.9 | 7382 | 191709 | 40.6 | 3.44 (3.34, 3.55)∗∗∗ | 3.08 (2.99, 3.18)∗∗∗ |
| 50-64 | 9290 | 312176 | 29.8 | 4160 | 63233 | 65.8 | 2.19 (2.11, 2.27)∗∗∗ | 2.18 (2.10, 2.26)∗∗∗ |
| 65+ | 5108 | 215649 | 23.7 | 2097 | 48229 | 43.5 | 1.82 (1.73, 1.91)∗∗∗ | 1.88 (1.79, 1.98)∗∗∗ |
| Comorbidity‡ | ||||||||
| No | 13645 | 1003452 | 13.6 | 10840 | 375347 | 28.9 | 3.40 (3.31, 3.49)∗∗∗ | 3.37 (3.28, 3.46)∗∗∗ |
| Yes | 8639 | 181008 | 47.7 | 5000 | 112164 | 44.6 | 1.57 (1.52, 1.62)∗∗∗ | 1.54 (1.49, 1.60)∗∗∗ |
PY: person-years; Rate#: incidence rate, per 1,000 person-years; Crude HR: crude hazard ratio; Adjusted HR†: multivariable analysis including age, sex, and comorbidities of hypertension, stroke, diabetes, COPD, CAD, alcohol-related illness, and asthma; Comorbidity‡: patients with any one of the comorbidities of hypertension, stroke, diabetes, COPD, CAD, alcohol-related illness, and asthma were classified as the comorbidity group. ∗∗∗P < 0.001.