Fig. 3. Effect of PF on the production of IL-6 (A), IL-1β (B), and TNF-α (C) in Aβ25–35-treated C6 glial cells. ‘Control’ represents non-treated cells, ‘Aβ’ represents Aβ25–35-treated cells, ‘PF1’, ‘PF5’, or ‘PF10’ represent the 3 concentrations of paeoniflorin treatment (1, 5, and 10 μg/mL, respectively) in Aβ25–35-treated cells. Values are mean ± SD.
IL, interleukin; Aβ, amyloid beta; PF, paeoniflorin; TNF-α, tumor necrosis factor-alpha.
a-cMeans with different letters are significantly different (P < 0.05) as determined by Duncan's multiple range test.